Metagenomics Data Analysis Services

Viral Metagenomics (Viromics) Data Analysis

Illuminate the hidden viral universe and uncover novel viruses, phage host dynamics, and diagnostic targets. Dawn of Bioinformatics Ltd. offers cutting edge viral metagenomics data analysis services to illuminate the hidden virosphere within clinical, environmental, and host associated samples. Our DawniLab experts specialize in virus discovery, viral genome assembly, and host range assignment from both DNA and RNA viromes, delivering comprehensive virome characterization that bypasses culture dependence and drastically compresses the path from sequence to actionable biological insight.

Viral Metagenomics (Viromics) Data Analysis

Overview

Dawn of Bioinformatics Ltd. provides advanced viral metagenomics analysis to illuminate the hidden virosphere in clinical specimens, environmental samples, and host associated communities. Our service encompasses discovery and assembly of both DNA and RNA viral genomes, taxonomic classification against comprehensive reference databases, and host prediction through integrated machine learning and motif matching. DawniLab's ensemble approach identifies novel phages and eukaryotic viruses, profiles virome diversity, and links viral populations to their bacterial or eukaryotic hosts, enabling fundamental discoveries and translational applications such as phage therapy candidate selection and diagnostic target development.

Key Features

✓ Viral sequence enrichment, quality filtering, and de novo genome assembly (metaSPAdes, VICUNA).
✓ Taxonomic classification using NCBI Viral RefSeq, IMG/VR, and protein clustering tools (vConTACT2, VPF Class).
✓ Host prediction via CRISPR spacer matching, oligonucleotide signatures, and integrated machine learning.
✓ Abundance profiling, alpha/beta diversity, and differential representation analysis of viral populations.

Demo & Results

From a healthy human gut virome we identified 2,500 viral contigs, including 150 complete phage genomes, 18 of which represented novel Siphoviridae genera. Host linkage analysis revealed that 40% of these phages selectively target Bacteroides species, providing a foundational candidate panel for future phage therapy research.

Frequently Asked Questions