Personalised Medicine & Pharmacogenomics
Optimize therapeutic efficacy and minimize adverse drug reactions by analyzing individual genetic variations. We provide predictive insights into drug metabolism to ensure precision prescribing tailored to every patient.
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Overview
Personalised Medicine ensures that the right drug is given to the right patient at the right dose. Through our Pharmacogenomics (PGx) service, we analyze an individual’s genetic variations to predict how they will metabolize specific medications. This allows clinicians to optimize therapeutic efficacy and minimize the risk of adverse drug reactions (ADRs), which are a leading cause of hospitalizations. By providing precision prescribing insights tailored to the patient’s unique genetic makeup, we transform medication management into a safer and more effective process.
Key Features
> Drug Metabolism Insights: Analyzing CYP450 and other key enzyme groups to determine metabolic speed.
> Adverse Reaction Prevention: Identifying genetic predispositions to severe drug side effects.
> Dosing Optimization: Providing data-backed recommendations for dose adjustments based on genotype.
> Cardiology & Psychiatry Panels: Specialized testing for medications where genetic variation has the highest impact.
> Lifetime Genetic Record: A one-time test that provides a reference for future medication needs.
Application & Demo
We partnered with a cardiology clinic to implement a pharmacogenomics screening program for patients starting Clopidogrel (a common blood thinner). Our analysis identified "poor metabolizers" (carriers of the CYP2C19*2 allele) who were at high risk for major adverse cardiovascular events because the drug would not be activated in their bodies. Based on our reports, 15% of the patients were switched to an alternative medication, effectively preventing potential treatment failures and secondary strokes.
Frequently Asked Questions
Does my DNA change over time?
No, your germline DNA remains the same, so your pharmacogenomic results are generally valid for your entire life.
Can this test tell me which antidepressant will work best?
It can identify which drugs you are likely to metabolize normally and which might cause side effects, helping your doctor narrow down the best options.
Is the test covered by insurance?
Many insurance providers now cover PGx testing, especially for patients on specific cardiovascular or psychiatric medications.
How is the sample collected?
It is a non-invasive process, usually requiring only a simple cheek swab.